IL1RN genotype as a risk factor for joint pain in hereditary haemochromatosis?
نویسندگان
چکیده
منابع مشابه
Screening for hereditary haemochromatosis.
Hereditary haemochromatosis (HH) is a common autosomal recessive disorder of iron overload in Caucasian populations. Clinical manifestations usually occur in individuals homozygous for the C282Y mutation in the HFE gene product and who have developed significant iron loading. Current screening methods can detect affected individuals either prior to or early during disease evolution, enabling ea...
متن کاملHereditary haemochromatosis.
Haemochromatosis should currently refer to hereditary iron overload disorders presenting with a definite and common phenotype characterised by normal erythropoiesis, increased transferrin saturation and ferritin and primarily parenchymal iron deposition related to innate low (but normally regulated) production of the hepatic peptide hormone hepcidin. Since the discovery of the haemochromatosis ...
متن کاملHereditary haemochromatosis
The May issue of the BJGP made my mouth fall open with disbelief. What was the leading article about?1 The latest NSF? The GPC resignation ballot? The Shipman inquiry? The recent spate of TB outbreaks? The RCGP’s ideas about GP specialists and intermediate care? 24/48 hour access? NICE and the relevance of its guidance to Primary Care? What to do with your free copy of Clinical Evidence? No. It...
متن کاملMetabolic Syndrome as a Risk Factor for Osteoarthritis
Metabolic syndrome refers to a set of conditions that include high blood pressure, increased insulin level in the blood, the accumulation of the excess fat around the abdomen, and increased blood lipids. In metabolic syndrome, the vast majority of these conditions are simultaneously present, and the risk of developing heart disease, stroke, and diabetes rises. Besides, osteoarthritis or degen...
متن کاملNon HFE related hereditary haemochromatosis.
Hereditary hemochromatosis (HH) is manifested as iron overload in different organs due to homozygosity of a single autosomal mutation. Two different mutations C282Y and H63D in the HFE gene have been associated with hereditary hemochromatosis cases. This disease is seen in northern european populations, but in India it is a rare disease. We report a young male with severe abnormalty of liver fu...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2006
ISSN: 0003-4967
DOI: 10.1136/ard.2005.038158